HES5 Polyclonal Antibody, 20ul Recombinant Ab Production Cytochrome c oxidase I (COX1)

Cytochrome c oxidase I (COX1) also known as mitochondrially encoded cytochrome c oxidase I (MT-CO1) is a protein that in humans is encoded by the MT-CO1 gene

Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene

Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known

This gene is part of a 500 kb inverted duplication on chromosome 5q13

Transcript heterogeneity due to alternative polyadenylation has been noted for this gene

HES5 Polyclonal Antibody, 20ul Recombinant Ab Production Cytochrome c oxidase I (COX1)This gene encodes a member of a family of basic helix loop helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.