Ksr2 Polyclonal Antibody, 100ul Cell Proliferation This gene encodes a bifunctional

This gene encodes a bifunctional signal transduction molecule

Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons

pathway:Lipid metabolism

Expression of the protein has been observed in various human cancer cell lines established from malignant tumors

Also expressed in Barrett's esophagus epithelium and in the proximal duodenum

Ksr2 Polyclonal Antibody, 100ul Cell Proliferation This gene encodes a bifunctionalLocation regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8 mediated signaling. Acts as a negative regulator of MAP3K3 mediated activation of ERK, JNK and NF kappa B pathways, inhibiting MAP3K3 mediated interleukin 8 production.