Bad Polyclonal Antibody, 50ul[BT-AP00810] Insect Expression The protein encoded by GAB2

The protein encoded by GAB2 is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor

1995) [PubMed 7606925]

The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis

Multiple alternatively spliced variants have been found in normal and cancerous tissues

This protein acts by binding with high affinity to the cell surface receptor

Bad Polyclonal Antibody, 50ul[BT-AP00810] Insect Expression The protein encoded by GAB2BCL2 associated agonist of cell death encoded by BAD is a member of the BCL 2 family. BCL 2 family members are known to be regulators of programmed cell death. BCL2 associated agonist of cell death positively regulates cell apoptosis by forming heterodimers with BCL xL and BCL 2, and reversing their death repressor activity. Proapoptotic activity of BCL2 associated agonist of cell death is regulated through its phosphorylation. Protein kinases AKT and