GDF8 Polyclonal Antibody, 100ul ADME CCDC45 (coiled-coil domain containing 45)

CCDC45 (coiled-coil domain containing 45) is a 821 amino acid protein encoded by a gene that maps to human chromosome 17q23

Its specific function has not been determined

Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene

These family members are transcription factors that are implicated in a variety of cellular processes

such as p53

GDF8 Polyclonal Antibody, 100ul ADME CCDC45 (coiled-coil domain containing 45)This gene encodes a secreted ligand of the TGF beta (transforming growth factor beta) superfamily of proteins. Ligands of this family bind various TGF beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide linked homodimer. This protein negatively regulates skeletal muscle cell proliferation