MAD1 Polyclonal Antibody, 50ul Antisense Oligonucleotides and thrombospondin N-terminal-like domains

and thrombospondin N-terminal-like domains

Mutations in this gene have been implicated in a neurodevelopmental disorder

The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes

The encoded protein contains a KRAB (Kruppel-associated box) domain -A box and a SET (Su(var)3-9| Enhancer-of-zeste| Trithorax) domain and may function as a histone methyltransferase

and osteogenic sarcoma

MAD1 Polyclonal Antibody, 50ul Antisense Oligonucleotides and thrombospondin N-terminal-like domainsMAD1L1 (MAD1 mitotic arrest deficient like 1) is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants.