Pan glycine myristoylation Polyclonal Antibody, 20ul Cellular Function Assays A translocation involving this gene

A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene| encoding a DNA binding protein| located on chromosome 11 is associated with leukemia

called nucleosomes

and studies in rat suggest that alternative use of the two translation initiation sites results in N-terminally distinct protein isoforms with different subcellular localization

This gene encodes human pituitary glutaminyl cyclase| which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides

Allelic variations in this gene have been associated| but not causally linked| with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS)

Pan glycine myristoylation Polyclonal Antibody, 20ul Cellular Function Assays A translocation involving this genePan3 (PAB dependent poly(A) specific ribonuclease subunit 3) is a 741 amino acid cytoplasmic protein belonging to the protein kinase superfamily. Containing a protein kinase domain, Pan3 is a component of the Pan nuclease complex and recruits polyadenylate binding protein, which in turn stimulates Pan2 nuclease activity. It is suggested that Pan3 may have a functional role in cytoplasmic mRNA decay. Pan3 exists as three isoforms produced by