Ezatiostat Hydrochloride Size:Solid 10 mg 2-(phenylsulfonyl)hydrazide

2-(phenylsulfonyl)hydrazide

ETC-159 has robust activity in multiple cancer models driven by high Wnt signaling

Chemical Name: 4-{3-[(1E)-2-[(3-bromophenyl)carbamoyl]-2-cyanoeth-1-en-1-yl]-2

JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines

InChiKey: YYLKKYCXAOBSRM-JXMROGBWSA-N

Ezatiostat Hydrochloride Size:Solid 10 mg 2-(phenylsulfonyl)hydrazideEzatiostat is a liposomal small molecule glutathione analog inhibitor of glutathione S transferase (GST) P1 1 with hematopoiesis stimulating activity. After intracellular de esterification, the active form of ezatiostat binds to and inhibits GST P1 1, thereby restoring Jun kinase and MAPK pathway activities and promoting MAPK mediated cellular proliferation and differentiation pathways. This agent promotes the proliferation and maturation of