Rottlerin - CAS# 82-08-6 size:10mg solid 74 ± 2 nM
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Rottlerin - CAS# 82-08-6 size:10mg solid 74 ± 2 nMRottlerin, CAS No. 82 08 6, is an angiogenesis inhibitor and an inhibitor of protein kinase Cdelta (PKCdelta) and calmodulin kinase III. Rottlerin as a novel chemotherapy agent for adrenocortical carcinoma. Rottlerin induces cyclooxygenase 2 upregulation through an ATF4 and reactive oxygen species independent pathway in HEI OC1 cells. Rottlerin exerts its anti tumor activity through inhibition of Skp2 in breast cancer cells. Rottlerin suppresses
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