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BMS-690514 Catalog No.:M10884-2 is a functionalized IAP ligand

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BMS-690514 Catalog No.:M10884-2 is a functionalized IAP ligandBMS 690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4, and vascular endothelial growth factor receptors (VEGFR) 1 3. BMS 690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo studies were conducted to characterize the pharmacokinetics and metabolism. Through integration of in vitro and in vivo pharmacokinetic data and antitumor efficacy in nude

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Description

is a functionalized IAP ligand for PROTACs

11-diazatetracyclo[7

1'-biphenyl]-4-yl]prop-2-enoic acid

Formula: C17H13N5O2

Formula: C24H20Cl2FN5O2

BMS-690514 Catalog No.:M10884-2 is a functionalized IAP ligandBMS 690514 is a potent inhibitor of human epidermal growth factor receptor (HER) 1 (EGFR), 2, and 4, and vascular endothelial growth factor receptors (VEGFR) 1 3. BMS 690514 is currently under investigation as an oral agent for the treatment of solid tumors. In vitro and in vivo studies were conducted to characterize the pharmacokinetics and metabolism. Through integration of in vitro and in vivo pharmacokinetic data and antitumor efficacy in nude

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