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GW311616 Size:Solid 10 mg Wnt-C59 displayed good bioavailability as

SKU: 51392539045

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PLN115.00 PLN151.00

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GW311616 Size:Solid 10 mg Wnt-C59 displayed good bioavailability asGW 311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase (HNE). Product information CAS Number: 198062 54 3 Molecular Weight: 397. 53 Formula: C19H31N3O4S Synonym: GW 311616 GW 311616 Chemical Name: (3S,3aS,6aR) 1 methanesulfonyl 4 [(2E) 4 (piperidin 1 yl)but 2 enoyl] 3 (propan 2 yl) octahydropyrrolo[3,2 b]pyrrol 2 one Smiles: CC(C)[C@H]1[C@H]2[C@@H](CCN2C(=O) C=C CN2CCCCC2)N(C1=O)S(C)(=O)=O

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Description

Wnt-C59 displayed good bioavailability as once daily oral administration and blocked progression of mammary tumors in MMTV-WNT1 transgenic mice model while downregulating Wnt/β-catenin target genes

PubMed PMID: 22366308

an enzyme often overexpressed in cancer cells

DeLucas LJ

BJE6-106 (B106) (0

GW311616 Size:Solid 10 mg Wnt-C59 displayed good bioavailability asGW 311616 is a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase (HNE). Product information CAS Number: 198062 54 3 Molecular Weight: 397. 53 Formula: C19H31N3O4S Synonym: GW 311616 GW 311616 Chemical Name: (3S,3aS,6aR) 1 methanesulfonyl 4 [(2E) 4 (piperidin 1 yl)but 2 enoyl] 3 (propan 2 yl) octahydropyrrolo[3,2 b]pyrrol 2 one Smiles: CC(C)[C@H]1[C@H]2[C@@H](CCN2C(=O) C=C CN2CCCCC2)N(C1=O)S(C)(=O)=O

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